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The most recent publication by my mentor Dr. Stuart Lipton and colleague Dr. Tomohiro Nakamura sheds new insight into the neurodegenerative effect of S-Nitrosylation.
The title of the publication is:
‘SNO’-Storms Compromise Protein Activity and Mitochondrial Metabolism in Neurodegenerative Disorders
https://doi.org/10.1016/j.tem.2017.10.004
They describe the effect of nitrosative/oxidative stress as a common mediator in Alzheimer’s Disease and Parkinson’s Disease.
Highly recommended!
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